Dr. Kartik T. Nakhate

Associate Professor & HOD

Qualification: M. Pharm., Ph.D.

Specialization: Pharmacology

Email ID:: kartik.nakhate@svkm.ac.in

Phone: +91-8223933802

Experience: 10 Years

• 04.05.2021 – Present:
  Institute : Shri Vile Parle Kelavani Mandal’s Institute of Pharmacy, Dhule, MH
  Position : Associate Professor of Pharmacology
• 01.08.2012 – 30.04.2021 (8.9 years):
  Institute : Rungta College of Pharmaceutical Sciences & Research, Bhilai, CG
  Position : Associate Professor of Pharmacology (02.07.2018 – 30.04.2021)
  Assistant Professor of Pharmacology (01.08.2012 – 01.07.2018)

Interest Areas: Neuropharmacology

Research:

• Publications:
  • International: 58
  • National: 01
• Books: Nil
• Book Chapters: 06
• Patents: 03
• Presentations:
  • International: 04
  • National: 12

Completed Government Funded Projects: 03

1. Role: Principal Investigator Area of Project: Neuropharmacology Name of Governing Body: SERB, Govt. of India

2. Role: Principal Investigator Area of Project: Neuropharmacology Name of Governing Body: ICMR, Govt. of India

3. Role: Co-Principal Investigator Area of Project: FIST Name of Governing Body: DST, Govt. of India

Industry Projects:

• Completed: Nil
• Ongoing: Nil

Conferences/Workshops/Seminars attended: 25

Academic Activities:

• Ph.D.
  • Awarded: 01
  • Registered: 03
• M. Pharm Guided: 17
• B. Pharm Guided: 40

Awards:

• Olson Prize (2013) sponsored by journal Peptides (ISSN: 0196-9781), Elsevier Inc. & the Department of Psychology, University of New Orleans, USA awarded for the most meritorious original research article on the behavioral effects of peptides [Article: ‘Nicotine evoked improvement in learning and memory is mediated through NPY Y1 receptors in rat model of Alzheimer's disease’ (Peptides 2012;33:317-328) by Rangani RJ, Upadhya MA, Nakhate KT, Kokare DM, Subhedar NK].
• P. P. Surya Kumari Prize at 45th Annual Conference of Indian Pharmacological Society & International Conference on Navigating Pharmacology towards the Safe and Effective Therapy, Nagpur (January 05-07, 2013) for the best publication from India on diabetes mellitus, other endocrinal and metabolic disorders [Article: ‘Effect of nicotine on feeding and body weight in rats: Involvement of cocaine-and amphetamine-regulated transcript peptide’ (Behavioural Brain Research 2011;219:31-38) by Dandekar MP, Nakhate KT, Kokare DM, Subhedar NK (First two authors contributed equally)].
• B. Uvnas Prize at 44th Annual Conference of Indian Pharmacological Society & Challenges Ahead in Translational Pharmacology, Manipal (December 19-21, 2011) for the best international publication from India on any aspect of autacoids and biogenic amines [Article: ‘Agmatine in the hypothalamic paraventricular nucleus stimulates feeding in rats: involvement of neuropeptide Y’ (British Journal of Pharmacology 2011;164:704-718) by Taksande BG, Kotagale NR, Nakhate KT, Mali PD, Kokare DM, Hirani K, Subhedar NK, Chopde CT, Ugale RR].
• Best Poster Award at 7th World Ayurveda Congress and Arogya Expo 2016 held by Society for Ethnopharmacology in association with Ministry of AYUSH; Government of India at Science City, Kolkata (December 1-4, 2016) [Article: ‘Plumbagin enhances spatial learning and memory in the mouse model of Alzheimer’s disease’ by Kokare DM and Nakhate KT].
• Prof. Govind Achari Prize for the Best Research Paper presented at 43rd Annual Conference of Indian Pharmacological Society & International Conference on Pharmacology and Translational Research, Hyderabad (December 13-16, 2010) [Article: ‘A role for cocaine- and amphetamine-regulated transcript peptide (CART) in morphine induced reward and reinforcement’ by Desai SJ, Upadhya MA, Nakhate KT, Kokare DM, Subhedar NK].
• Prof. Govind Achari Prize for the Best Research Paper presented at International Conference on Translational Pharmacology & 41st Annual Conference of Indian Pharmacological Society, New Delhi (December 18-20, 2008) [Article: ‘Evidence for involvement of corticotropin-releasing factor (CRF) 2 receptors in acute, chronic and withdrawal responses of nicotine on feeding behavior in rats’ by Upadhya MA, Nakhate KT, Kamdi SP, Dandekar MP, Kokare DM, Subhedar NK].
• Nominee of CPCSEA (Committee for the Purpose of Control and Supervision of Experiments on Animals), Ministry of Fisheries, Animal Husbandry and Dairying, Government of India, New Delhi
• Seminar Grant: Funding agency: ICMR [Reference: 7/525/17-Seminars (HRD)]

Professional Membership:

• Life member of the Indian Academy of Neuroscience (LN 35)
• Life member of the Indian Pharmacological Society (LN 86)
• Life member of the Association of Pharmaceutical Teachers of India (MA/LM-2617)
• Life member of the Indian Pharmaceutical Association (MAH/DHUL/ON/LM/000096)
• Life member of the Indian Pharmacy Graduates Association (LM 3090)
• Registered Pharmacist in the Maharashtra State Pharmacy Council (64239)

Recent Publications: 

1. Nakhate KT, Badwaik H, Choudhary R, Sakure K, Agrawal YO, Sharma C, Ojha S, Goyal SN. Therapeutic potential and pharmaceutical development of a multitargeted flavonoid phloretin. Nutrients 2022;14(17):3638 [Impact factor: 6.706].

2. Badwaik HR, Kumari L, Maiti S, Sakure K, Ajazuddin, Nakhate KT, Tiwari V, Giri T. A review on challenges and issues with carboxymethylation of natural gums: The widely used excipients for conventional and novel dosage forms. International Journal of Biological Macromolecules 2022;209(PtB):2197-2212 [Impact factor: 6.953].

3. Khichariya A, Jeswani G, Choudhary R, Alexander A, Nakhate KT, Badwaik HR. Formulation of plumbagin-loaded microemulsion: Evaluation of anti-rheumatoid efficacy in Wistar rat model. Journal of Molecular Liquids 2022;363:119851 [Impact factor: 6.633].

4. Agrawal Y, Patil K, Mahajan H, Potdar M, Joshi P, Nakhate K, Sharma C, Goyal SN, Ojha S. In vitro and in vivo characterization of Entacapone-loaded nanostructured lipid carriers developed by quality-by-design approach. Drug Delivery 2022;29(1):1112-1121 [Impact factor: 6.819].

5. Rani S, Sahoo RK, Kumar V, Chaurasiya A, Kulkarni O, Mahale A, Katke S, Kuche K, Yadav V, Jain S, Nakhate KT, Ajazuddin, Gupta U. HPMA-PCL Polymeric Micelles in Co-delivery of Proteasome Inhibitor and Polyphenol: Exploration of Synergism or Antagonism. Molecular Pharmaceutics 2022 [Impact factor: 5.364].

6. Pawar GR, Agrawal YO, Nakhate KT, Patil CR, Sharma C, Ojha S, Mahajan UB, Goyal SN. Ghrelin alleviates depression-like behaviour in rats subjected to high-fat diet and diurnal rhythm disturbance. American Journal of Translational Research 2022 [Impact factor: 3.940].

7. Rathod S, Agrawal Y, Sherikar A, Nakhate KT, Patil CR, Nagoor Meeran MF, Ojha S, Goyal SN. Thymoquinone produces cardioprotective effect in β-receptor stimulated myocardial infarcted rats via subsiding oxidative stress and inflammation. Nutrients. 2022;14(13):2742 [Impact factor: 6.706].

8. Pawar H, Mahajan UB, Nakhate KT, Agrawal YO, Patil CR, Nagoor Meeran MF, Sharma C, Ojha S, Goyal SN. Curcumin protects diabetic mice against isoproterenol-induced myocardial infarction by modulating CB2 cannabinoid receptors. Life 2022;12(5):624 [Impact factor: 3.251].

9. Rana R, Rani S, Kumar V, Nakhate KT, Ajazuddin, Gupta U. Sialic acid conjugated chitosan nanoparticles: modulation to target tumour cells and therapeutic opportunities. AAPS PharmSciTech 2022;23(1):10 [Impact factor: 4.026].

10. Jeswani G, Chablani L, Gupta U, Sahoo RK, Nakhate KT, Ajazuddin. Development and optimization of paclitaxel loaded Eudragit/PLGA nanoparticles by simplex lattice mixture design: Exploration of improved hemocompatibility and in vivo kinetics. Biomedicine & Pharmacotherapy 2021;144:112286 [Impact factor: 7.419].

11. Kamdi SP, Badwaik HR, Raval A, Ajazuddin, Nakhate KT. Ameliorative potential of phloridzin in type 2 diabetes-induced memory deficits in rats. European Journal of Pharmacology 2021;913:174645 [Impact factor: 5.195].

12. Kamdi SP, Raval A, Nakhate KT. Phloridzin attenuates lipopolysaccharide-induced cognitive impairment via antioxidant, anti-inflammatory and neuromodulatory activities. Cytokine 2021;139:155408 [Impact factor: 3.861].

13. Arora SK, Verma PR, Itankar PR, Prasad S, Nakhate KT. Evaluation of pancreatic regeneration activity of Tephrosia purpurea leaves in rats with streptozotocin-induced diabetes. Journal of Traditional and Complementary Medicine 2021;11(5):435-445 [Impact factor: 4.221].

14. Rani S, Sahoo RK, Nakhate KT, Ajazuddin, Gupta U. Biotinylated HPMA centered polymeric nanoparticles for bortezomib delivery. International Journal of Pharmaceutics 2020;579:119173 [Impact factor: 5.875].

15. Sahoo RK, Gothwal A, Rani S, Nakhate KT, Ajazuddin, Gupta U. PEGylated Dendrimer Mediated Delivery of Bortezomib: Drug Conjugation versus Encapsulation. International Journal of Pharmaceutics 2020;584:119389 [Impact factor: 5.875].

16. Advani K, Batra M, Tajpuriya S, Gupta R, Saraswat A, Nagar HD, Makwana L, Kshirsagar S, Kaul P, Ghosh AK, Pradhan S, Mehta A, Jaiswal A, Nakhate KT, Kamdi S. Efficacy of combination therapy of inositols, antioxidants and vitamins in obese and non-obese women with polycystic ovary syndrome: an observational study. Journal of Obstetrics and Gynaecology 2020;40(01):96-101 [Impact factor: 1.246].