Dr. Sameer N. Goyal

Professor & Principal

Qualification: Ph.D (AIIMS, New Delhi); PDF (USA)

Specialization: Pharmacology

Email ID: sameer.goyal@svkm.ac.in

Phone: +91-9552916993

Experience: 18.5 Years

• 27.06.2017– Present:
  Institute : Shri Vile Parle Kelavani Mandal’s Institute of Pharmacy, Dhule, MH
  Position : Professor & Principal
• 01.02.2013 – 26.06.2017:
  Institute : R. C. Patel Institute of Pharmaceutical Education and Research, Karwand Naka, Shirpur, Dist- Dhule, Maharashtra (425405)
  Position : Associate Professor
• 17.11.2009 – 30.01.2013:
  Industry: Scientific Analytics Team at BioXcel Corporation, Gurgaon
  Position : Assistant Manager
• 01.01.2009 – 15.11.2009:
  Research: (Translational Medicine, Department of Biomedical Sciences): Creighton University, Omaha, NE, USA (2009- 2010).
  Position : Post-doctoral Research Fellow
• 06.01.2006 – 30.12.2008:
  Research: Senior Research Fellow in ICMR-funded project
  Position : Senior Research Fellow

Interest Areas: Cardiovascular Pharmacology

Research:

• Publications:
  • International: 97
  • National: 02
• Books: 00
• Book Chapters: 03
• Patents: 00
• Presentations:
  • International: 02
  • National: 10
• Completed Government Funded Projects: 06

Industry Projects:

• Completed: 01
• Ongoing: Nil

Conferences/Workshops/Seminars attended: 25

Academic Activities:

• Ph.D.:
  • Awarded: 0
  • Registered: 03
• M. Pharm Guided: 15
• B. Pharm Guided: 20

Awards:

Professional Membership:

• Life Time Member of ‘Association of Pharmaceutical Teachers of India’(APTI)MA/LM—2525
• Lifetime member of The Indian Pharmaceutical Association (IPA) Membership No. MAH/DHUL/LM/0036

Recent Publications:

Nakhate KT, Badwaik H, Choudhary R, Sakure K, Agrawal YO, Sharma C, Ojha S, Goyal SN. Therapeutic Potential and Pharmaceutical Development of a Multitargeted Flavonoid Phloretin. Nutrients. 2022 Sep 2;14(17):3638. doi: 10.3390/nu14173638. PMID: 36079895; PMCID: PMC9460114. (Impact factor:5.719)

Agrawal YO, Husain M, Patil KD, Sodgir V, Patil TS, Agnihotri VV, Mahajan HS, Sharma C, Ojha S, Goyal SN. Verapamil hydrochloride loaded solid lipid nanoparticles: Preparation, optimization, characterisation, and assessment of cardioprotective effect in experimental model of myocardial infarcted rats. Biomed Pharmacother. 2022 Oct;154:113429. doi: 10.1016/j.biopha.2022.113429. Epub 2022 Aug 22. PMID: 36007280. (Impact factor:7.419)

Rathod S, Agrawal Y, Sherikar A, Nakhate KT, Patil CR, Nagoor Meeran MF, Ojha S, Goyal SN. Thymoquinone Produces Cardioprotective Effect in β-Receptor Stimulated Myocardial Infarcted Rats via Subsiding Oxidative Stress and Inflammation. Nutrients. 2022 Jun 30;14(13):2742. doi: 10.3390/nu14132742. PMID: 35807920; PMCID: PMC9268596. (Impact factor: 5.719)

Masule MV, Rathod S, Agrawal Y, Patil CR, Nakhate KT, Ojha S, Goyal SN, Mahajan UB. Ghrelin mediated regulation of neurosynaptic transmitters in depressive disorders. Curr Res Pharmacol Drug Discov. 2022 Jun 13;3:100113. doi: 10.1016/j.crphar.2022.100113. PMID: 35782191; PMCID: PMC9240712.

Agnihotri V, Agrawal Y, Goyal S, Sharma C, Ojha S. An Update on Advancements and Challenges in Inhalational Drug Delivery for Pulmonary Arterial Hypertension. Molecules. 2022 May 29;27(11):3490. doi: 10.3390/molecules27113490. PMID: 35684428; PMCID: PMC9182169. (Impact factor:4.927)

Pawar HD, Mahajan UB, Nakhate KT, Agrawal YO, Patil CR, Meeran MFN, Sharma C, Ojha S, Goyal SN. Curcumin Protects Diabetic Mice against Isoproterenol-Induced Myocardial Infarction by Modulating CB2 Cannabinoid Receptors. Life (Basel). 2022 Apr 22;12(5):624. doi: 10.3390/life12050624. PMID: 35629293; PMCID: PMC9143027. (Impact factor:3.251)

Eddin LB, Jha NK, Goyal SN, Agrawal YO, Subramanya SB, Bastaki SMA, Ojha S. Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol. Nutrients. 2022 Mar 25;14(7):1370. doi: 10.3390/nu14071370. PMID: 35405982; PMCID: PMC9002489. (Impact factor: 5.719)

Agrawal Y, Patil K, Mahajan H, Potdar M, Joshi P, Nakhate K, Sharma C, Goyal SN, Ojha S. In vitro and in vivo characterization of Entacapone- loaded nanostructured lipid carriers developed by quality-by-design approach. Drug Deliv. 2022 Dec;29(1):1112-1121. doi: 10.1080/10717544.2022.2058651. PMID: 35380091; PMCID: PMC8986208. (Impact factor:6.819 )

Sherikar A, Siddique MUM, More M, Goyal SN, Milivojevic M, Alkahtani S, Alarifi S, Hasnain MS, Nayak AK. Preparation and Evaluation of Silymarin-Loaded Solid Eutectic for Enhanced Anti-Inflammatory, Hepatoprotective Effect: In Vitro-In Vivo Prospect. Oxid Med Cell Longev. 2021 Nov 10;2021:1818538 (Impact factor: 6.543)

Hashiesh HM, Sharma C, Goyal SN, Jha NK, Ojha S. Pharmacological Properties, Therapeutic Potential and Molecular Mechanisms of JWH133, a CB2 Receptor-Selective Agonist. Front Pharmacol. 2021 Jul 30;12:702675. doi: 10.3389/fphar.2021.702675. eCollection 2021. PMID: 34393784 (Impact factor: 5.810)

Hashiesh HM, Jha NK, Sharma C, Gupta PK, Jha SK, Patil CR, Goyal SN, Ojha SK. Pharmacological potential of JWH133, a cannabinoid type 2 receptor agonist in neurodegenerative, neurodevelopmental and neuropsychiatric diseases. Eur J Pharmacol. 2021 Oct 15;909:174398. doi: 10.1016/j.ejphar.2021.174398. Epub 2021 Jul 29. PMID: 34332924 (Impact factor: 4.432)

Sharma C, Jha NK, Meeran MFN, Patil CR, Goyal SN, Ojha S. Serratiopeptidase, A Serine Protease Anti-Inflammatory, Fibrinolytic, and Mucolytic Drug, Can Be a Useful Adjuvant for Management in COVID-19. Front Pharmacol. 2021 Jun 24;12:603997. doi: 10.3389/fphar.2021.603997. eCollection 2021. PMID: 34248612 (Impact factor: 5.810)

Arunachalam S, Nagoor Meeran MF, Azimullah S, Sharma C, Goyal SN, Ojha S. Nerolidol Attenuates Oxidative Stress, Inflammation, and Apoptosis by Modulating Nrf2/MAPK Signaling Pathways in Doxorubicin-Induced Acute Cardiotoxicity in Rats. Antioxidants (Basel). 2021 Jun 21;10(6):984. doi: 10.3390/antiox10060984. PMID: 34205494 (Impact factor: 6.312)

Meeran MFN, Azimullah S, Mamoudh HH, Sharma C, Kumar S, Goyal SN, Ojha S. Nerolidol, a Sesquiterpene from the Essential Oils of Aromatic Plants, Attenuates Doxorubicin-Induced Chronic Cardiotoxicity in Rats. J Agric Food Chem. 2021 Jul 7;69(26):7334-7343. doi: 10.1021/acs.jafc.0c05667. Epub 2021 Jun 25. PMID: 34170670 (Impact factor: 5.279)

Hashiesh HM, Sharma C, Goyal SN, Sadek B, Jha NK, Kaabi JA, Ojha S. A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid. Biomed Pharmacother. 2021 Aug;140:111639. doi: 10.1016/j.biopha.2021.111639. Epub 2021 Jun 3. PMID: 34091179 (Impact factor: 6.529)

Jha NK, Sharma C, Hashiesh HM, Arunachalam S, Meeran MN, Javed H, Patil CR, Goyal SN, Ojha S. β-Caryophyllene, A Natural Dietary CB2 Receptor Selective Cannabinoid can be a Candidate to Target the Trinity of Infection, Immunity, and Inflammation in COVID-19. Front Pharmacol. 2021 May 14;12:590201. doi: 10.3389/fphar.2021.590201. eCollection 2021. PMID: 34054510 (Impact factor: 5.810)

Agrawal YO, Mahajan UB, Agnihotri VV, Nilange MS, Mahajan HS, Sharma C, Ojha S, Patil CR, Goyal SN. Ezetimibe-Loaded Nanostructured Lipid Carrier Based Formulation Ameliorates Hyperlipidaemia in an Experimental Model of High Fat Diet. Molecules. 2021 Mar 9;26(5):1485. doi: 10.3390/molecules26051485. (Impact factor: 3.267)

Nagoor Meeran MF, Javed H, Sharma C, Goyal SN, Kumar S, Jha NK, Ojha S. Can Echinacea be a potential candidate to target immunity, inflammation, and infection - The trinity of coronavirus disease 2019. Heliyon. 2021 Feb;7(2):e05990. doi: 10.1016/j.heliyon.2021.e05990. Epub 2021 Feb 8. (Impact factor: 1.650)

Meeran MFN, Laham F, Azimullah S, Sharma C, Al Kaabi AJ, Tariq S, Adeghate E, Goyal SN, Ojha S. β-Caryophyllene, a natural bicyclic sesquiterpene attenuates β-adrenergic agonist-induced myocardial injury in a cannabinoid receptor-2 dependent and independent manner. Free Radic Biol Med. 2021 May 1;167:348-366. doi: 10.1016/j.freeradbiomed.2021.01.046. Epub 2021 Feb 13. (Impact factor: 6.170)

Nagoor Meeran MF, Seenipandi A, Javed H, Sharma C, Hashiesh HM, Goyal SN, Jha NK, Ojha S. Can limonene be a possible candidate for evaluation as an agent or adjuvant against infection, immunity, and inflammation in COVID-19? Heliyon. 2020 Dec 11;7(1):e05703. (Impact factor: 1.650)

Meeran MFN, Azimullah S, Al Ahbabi MM, Jha NK, Lakshmanan VK, Goyal SN, Ojha S. Nootkatone, a Dietary Fragrant Bioactive Compound, Attenuates Dyslipidemia and Intramyocardial Lipid Accumulation and Favorably Alters Lipid Metabolism in a Rat Model of Myocardial Injury: An In Vivo and In Vitro Study. Molecules. 2020 Nov 30;25(23):5656. (Impact factor: 3.267)

Chalikwar SS, Surana SJ, Goyal SN, Chaturvedi KK, Dangre PV. Solid self-microemulsifying nutraceutical delivery system for hesperidin using quality by design: assessment of biopharmaceutical attributes and shelf-life. J Microencapsul. 2021 Jan;38(1):61-79. (Impact factor: 2.287)

Nagoor Meeran MF, Sharma C, Goyal SN, Kumar S, Ojha S. CB2 receptor-selective agonists as candidates for targeting infection, inflammation, and immunity in SARS-CoV-2 infections. Drug Dev Res. 2020 Nov 15. doi: 10.1002/ddr.21752. Epub ahead of print. PMID: 33190277. (Impact factor: 1.902)

Patil AS, Mahajan UB, Agrawal YO, Patil KR, Patil CR, Ojha S, Sharma C, Goyal SN. Plant-derived natural therapeutics targeting cannabinoid receptors in metabolic syndrome and its complications: A review. Biomed Pharmacother. 2020 Dec;132:110889. doi: 10.1016/j.biopha.2020.110889. Epub 2020 Oct 28. PMID: 33113429. (Impact factor: 4.545 )

Birari L, Wagh S, Patil KR, Mahajan UB, Unger B, Belemkar S, Goyal SN, Ojha S, Patil CR. Aloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative stress and pro-inflammatory cytokines. Cancer Chemother Pharmacol. 2020 Sep;86(3):419-426. doi: 10.1007/s00280-020-04125-w. Epub 2020 Aug 18. PMID: 32812061. (Impact factor: 2.967)

Birari LA, Mahajan UB, Patil KR, Patil DD, Bagul NA, Belemkar S, Goyal SN, Ojha S, Patil CR. Aloin protects against arsenic trioxide-induced myocardial membrane damage and release of inflammatory cytokines. Naunyn Schmiedebergs Arch Pharmacol. 2020 Feb 6. (Impact factor-2.238)

Nagoor Meeran MF, Azimullah S, Laham F, Tariq S, Goyal SN, Adeghate E, Ojha S. α-Bisabolol protects against β-adrenergic agonist-induced myocardial infarction in rats by attenuating inflammation, lysosomal dysfunction, NLRP3 inflammasome activation and modulating autophagic flux. Food Funct. 2020 Jan 29;11(1):965-976. (Impact factor-3.241)